Theranos went from one of the most lauded “unicorn” tech startups in Silicon Valley to a company crippled by scandal.

Elizabeth Holmes, Theranos’ founder and CEO, dropped out of Stanford University to launch the company in 2003 as a cheaper, more efficient alternative to traditional medical tests. It promised patients the ability to test for conditions like cancer and diabetes with just a few drops of blood.

But questions swirled over its testing and technology. Investigations ensued. And on Friday, Holmes was charged by the US government with wire fraud and conspiracy to commit wire fraud. She faces up to 20 years in prison if convicted.

Here’s a look back at the rise and fall of Elizabeth Holmes and her blood testing startup.

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